| PRODUCT NAME:Albendazole Tablets | |
| STRENGTH:200mg/table | |
| PACKING DETAILS:10*10tables/box | |
| STORAGE:Store in a cool and dry place below 25oC, protected from light. | |
| SHELF LIFE:24 months | |
| REGISTRATION DOSSIERS ARE AVAILABLE. | |
| CONSIGNMENT MANUFACTURING, BRAND OEM/ODM SERVICE IS AVAILABLE. | |
Albendazole exerts its therapeutic effects primarily through its active metabolite, albendazole sulfoxide. This metabolite selectively disrupts the microtubule structures within the cells of parasites, particularly those in the intestinal cells and cortical layers. By binding to the β-tubulin subunits in the parasite's microtubules, it inhibits microtubule polymerization, thereby interfering with the intracellular transport and nutrient absorption of the parasites. Additionally, albendazole reduces the uptake of glucose by parasites, depleting their glycogen reserves, which ultimately leads to energy exhaustion, paralysis, and death of the parasites.
At higher concentrations, albendazole can also inhibit key metabolic enzymes, such as malate dehydrogenase and fumarate reductase, disrupting the metabolic pathways of parasites and further reducing ATP production. This leads to the inability of parasites to maintain normal physiological functions. This mechanism of action allows albendazole to be effective against a wide range of parasites while having minimal impact on host cells.
Albendazole tablets are a broad-spectrum antiparasitic medication, widely used to treat various parasitic infections. The main applications include:
The dosage of albendazole tablets varies depending on the type of infection and the patient's age:
Albendazole tablets should be stored in a tightly closed container, kept in a dry and cool place, and protected from direct sunlight. They are typically recommended to be stored at room temperature (15°C to 30°C).
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